Anyone experience mail defer only happen on particular user. No matter send from internal or external some of mail to the particular user will defer. From message tracking log found below message on recipient Status
"432 4.2.0 STOREDRV.Deliver.Exception:StorageTransientException.MapiExceptionTimeout; Failed to process message due to a transient exception with message Can't get receive folder. 16.55847:89000000, 17.43559:01040480A20000000000000059EA000000000000, 4.32881:01040480, 0.50035:00000000, 4.64625:01040480, 20.52176:000F91831600F01F000F9183, 20.50032:000F91838417F01F07000000, 0.50128:80030400, 255.1494:18000000, 4.43632:01040480, 4.58656:01040480, 4.35992:01040480, 255.1750:0F010480, 255.1494:FA000000, 4.43632:01040480, 4.58656:01040480, 4.35992:01040480, 255.1750:302E3039, 0.50288:30303A4D, 4.23354:01040480, 0.25913:05000780, 255.21817:01040480, 0.21934:0F010480, 4.27054:01040480 [Stage: OnPromotedEvent][Agent: Mailbox Rules Agent]"